|Product Description||Goat polyclonal antibody to 14-3-3 sigma|
|Background||Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway. p53-regulated inhibitor of G2/M progression. |
|Synonyms||YWHAS, 14-3-3sigma, SFN, 1433sigma, 1433 sigma / Stratifin, HGNC:10773, stratifin|
|Cellular Localization||May be secreted by a non-classical secretory pathway. |
|Specificity||This antibody is specific for 14-3-3 sigma / Stratifin.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Dog, Pig|