14-3-3 theta antibody
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||28 kDa (note)
|Positive Controls||293T , A431 , HeLa , HepG2 , H1299 , HeLaS3 , Molt-4 , Raji , mouse brain|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide|
|Product Description||Rabbit Polyclonal antibody to 14-3-3 theta (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide)|
|Background||This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease. [provided by RefSeq]|
|Synonyms||2014/3/3 antibody, 1C5 antibody, HS1 antibody, YWHAQ antibody, 14-3-3 protein T-cell antibody, 14-3-3 protein theta antibody, protein tau antibody, 14-3-3 protein tau antibody, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human 14-3-3 theta. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Xenopus laevis, Rabbit, Chicken, Bovine|
|Predict Reactivity Note||Rat (99%), Xenopus laevis (80%), Rabbit (99%), Chicken (99%), Bovine (100%)|