14-3-3 zeta antibody
|Applications||ICC/IF, IHC-P, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||28 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLaS3 , HepG2 , Molt-4 , Raji , NIH-3T3|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide|
|Product Description||Rabbit Polyclonal antibody to 14-3-3 zeta (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide)|
|Background||This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene. [provided by RefSeq]|
|Synonyms||14-3-3-zeta antibody, KCIP-1 antibody, MGC111427 antibody, MGC126532 antibody, MGC138156 antibody, YWHAD antibody, YWHAZ antibody, phospholipase A2 antibody, 14-3-3 zeta antibody, protein kinase C inhibitor protein-1 antibody, 14-3-3 delta antibody, 14-3-3 protein zeta/delta antibody, 14-3-3 protein/cytosolic phospholipase A2 antibody, protein kinase C inhibitor protein 1 antibody, "tyrosine 3/tryptophan 5 -monooxygenase activation protein, zeta polypeptide antibody", "tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, delta polypeptide antibody", "tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide antibody"|
|Cellular Localization||Cytoplasm , Melanosome |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human 14-3-3 zeta. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Zebrafish, Xenopus laevis, Pig, Chicken, Sheep, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Rat (99%), Zebrafish (80%), Xenopus laevis (89%), Pig (99%), Chicken (99%), Sheep (99%), Rhesus Monkey (100%), Bovine (100%)|