|Full Name||eukaryotic translation initiation factor 4E binding protein 1|
|Product Description||Rabbit Polyclonal antibody to 4E-BP1 (eukaryotic translation initiation factor 4E binding protein 1)|
|Background||This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq]|
|Synonyms||4E-BP1 antibody, 4EBP1 antibody, BP-1 antibody, MGC4316 antibody, PHAS-I antibody, EIF4EBP1 antibody, eukaryotic translation initiation factor 4E-binding protein 1 antibody, eIF4E-binding protein 1 antibody, phosphorylated heat- and acid-stable protein regulated by insulin 1 antibody, eukaryotic translation initiation factor 4E binding protein 1 antibody|
|Immunogen||Full length human 4E-BP1 Recombinant protein.|
|Species Reactivity||Human, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Pig, Bovine|
|Predict Reactivity Note||Mouse (90%), Pig (91%), Bovine (92%)|