|Full Name||5-hydroxytryptamine (serotonin) receptor 1B|
|Product Description||Rabbit Polyclonal antibody to 5-HT1B receptor|
|Background||The neurotransmitter serotonin (5-hydroxytryptamine; 5-HT) exerts a wide variety of physiologic functions through a multiplicity of receptors and may be involved in human neuropsychiatric disorders such as anxiety, depression, or migraine. These receptors consist of 4 main groups, 5-HT-1, 5-HT-2, 5-HT-3, and 5-HT4, subdivided into several distinct subtypes on the basis of their pharmacologic characteristics, coupling to intracellular second messengers, and distribution within the nervous system (Zifa and Fillion, 1992 [PubMed 1359584]). The serotonergic receptors belong to the multigene family of receptors coupled to guanine nucleotide-binding proteins.[supplied by OMIM]|
|Synonyms||5-HT1B antibody, 5-HT1DB antibody, HTR1D2 antibody, HTR1DB antibody, S12 antibody, HTR1B antibody, serotonin 1D beta receptor antibody, serotonin receptor 1B antibody, 5-HT-1D-beta antibody, 5-hydroxytryptamine receptor 1B antibody, 5-HT-1B antibody, 5-hydroxytryptamine (serotonin) receptor 1B antibody|
|Cellular Localization||Cell membrane |
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human 5HT1B Receptor. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Dog, Cat, Pig, Rabbit, Chimpanzee|
|Predict Reactivity Note||Mouse (100%), Rat (100%), Dog (100%), Cat (100%), Pig (100%), Rabbit (100%), Chimpanzee (100%)|