|Full Name||ATP-binding cassette, sub-family B (MDR/TAP), member 7|
|Product Description||Rabbit polyclonal antibody to ABCB7 (ATP-binding cassette, sub-family B (MDR/TAP), member 7)|
|Background||The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a half-transporter involved in the transport of heme from the mitochondria to the cytosol. With iron/sulfur cluster precursors as its substrates, this protein may play a role in metal homeostasis. Mutations in this gene have been implicated in X-linked sideroblastic anemia with ataxia. [provided by RefSeq]|
|Synonyms||ABC7 antibody, ASAT antibody, Atm1p antibody, EST140535 antibody, ABCB7 antibody, ATP-binding cassette 7 antibody, ABC transporter 7 protein antibody, ATP-binding cassette transporter 7 antibody, "ATP-binding cassette sub-family B member 7, mitochondrial antibody", "ATP-binding cassette, sub-family B (MDR/TAP), member 7 antibody"|
|Cellular Localization||Mitochondrion inner membrane |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human ABCB7. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Rat (98%), Bovine (97%)|