|Full Name||ATP-binding cassette, sub-family D (ALD), member 4|
|Product Description||Rabbit Polyclonal antibody to ABCD4 (ATP-binding cassette, sub-family D (ALD), member 4)|
|Background||The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that it may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxisome biogenesis. Alternative splicing results in at least two different transcript variants, one which is protein-coding and one which is probably not protein-coding. [provided by RefSeq]|
|Synonyms||ABC41 antibody, EST352188 antibody, P70R antibody, P79R antibody, PMP69 antibody, PXMP1L antibody, ABCD4 antibody, PXMP1-L antibody, ATP-binding cassette sub-family D member 4 antibody, 69 kDa peroxisomal ABC-transporter antibody, PMP70-related protein antibody, peroxisomal membrane protein 69 antibody, ATP-binding cassette, sub-family D (ALD), member 4 antibody|
|Cellular Localization||Peroxisome membrane |
|Immunogen||Recombinant protein encompassing a sequence within the C-terminus region of human ABCD4. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Mouse (91%), Rat (92%)|