|Full Name||ATP-binding cassette, sub-family E (OABP), member 1|
|Product Description||Rabbit Polyclonal antibody to ABCE1 (ATP-binding cassette, sub-family E (OABP), member 1)|
|Background||The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]|
|Synonyms||ABC38 antibody, OABP antibody, RLI antibody, RNASEL1 antibody, RNASELI antibody, RNS4I antibody, ABCE1 antibody, 2'-5'-oligoadenylate-binding protein antibody, ATP-binding cassette sub-family E member 1 antibody, huHP68 antibody, ribonuclease 4 inhibitor antibody, RNase L inhibitor antibody, ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) inhibitor antibody, ATP-binding cassette, sub-family E (OABP), member 1 antibody|
|Cellular Localization||Cytoplasm , Mitochondrion|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human ABCE1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Zebrafish, Chicken, Rhesus Monkey, Chimpanzee, Bovine|
|Predict Reactivity Note||Mouse (100%), Rat (99%), Zebrafish (85%), Chicken (98%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (100%)|