|Full Name||v-abl Abelson murine leukemia viral oncogene homolog 2|
|Product Description||Rabbit Polyclonal antibody to ABL2 (v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene))|
|Background||This gene encodes a member of the Abelson family of nonreceptor tyrosine protein kinase. The protein is highly similar to the ABL1 protein, including the tyrosine kinase, SH2 and SH3 domains, and has a role in cytoskeletal rearrangements by its C-terminal F-actin- and microtubule-binding sequences. This gene is expressed in both normal and tumor cells, and is involved in translocation with the ETV6 gene in leukemia. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq]|
|Synonyms||ABLL antibody, ARG antibody, FLJ22224 antibody, FLJ31718 antibody, FLJ41441 antibody, ABL2 antibody, abelson-related gene protein antibody, Abelson tyrosine-protein kinase 2 antibody, tyrosine-protein kinase ARG antibody, v-abl Abelson murine leukemia viral oncogene homolog 2 antibody|
|Cellular Localization||Cytoplasm , cytoskeleton |
|Specificity||Knockdown/Knockout validation was supported by references (PMID:27293031)|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human ABL2. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Zebrafish, Xenopus laevis, Bovine|
|Predict Reactivity Note||Mouse (99%), Rat (99%), Zebrafish (96%), Xenopus laevis (96%), Bovine (99%)|