|Full Name||amiloride-sensitive cation channel 4, pituitary|
|Product Description||Rabbit polyclonal antibody to ACCN4 (amiloride-sensitive cation channel 4, pituitary)|
|Background||This gene belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. This gene is predominantly expressed in the pituitary gland, and was considered a candidate for paroxysmal dystonic choreoathetosis (PDC), a movement disorder, however, no correlation was found between mutations in this gene and PDC. Alternative splicing at this locus results in two transcript variants encoding different isoforms. [provided by RefSeq]|
|Synonyms||ASIC4 antibody, BNAC4 antibody, MGC17248 antibody, MGC24860 antibody, ACCN4 antibody, amiloride-sensitive cation channel 4 antibody, acid-sensing ion channel 4 antibody, brain sodium channel 4 antibody, "amiloride-sensitive cation channel 4, pituitary antibody"|
|Cellular Localization||Membrane |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human ACCN4. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Rabbit|
|Predict Reactivity Note||Mouse (96%), Rat (96%), Rabbit (95%)|