|Full Name||angiotensin I converting enzyme (peptidyl-dipeptidase A) 1|
|Product Description||Rabbit Polyclonal antibody to ACE (angiotensin I converting enzyme (peptidyl-dipeptidase A) 1)|
|Background||This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes - the somatic form and the testicular form that are equally active. Multiple additional alternatively spliced variants have been identified but their full length nature has not been determined. [provided by RefSeq]|
|Synonyms||ACE1 antibody, CD143 antibody, DCP antibody, DCP1 antibody, MGC26566 antibody, MVCD3 antibody, ACE antibody, dipeptidyl carboxypeptidase 1 antibody, angiotensin-converting enzyme antibody, carboxycathepsin antibody, peptidase P antibody, dipeptidyl carboxypeptidase I antibody, kininase II antibody, "angiotensin converting enzyme, somatic isoform antibody", CD143 antigen antibody, testicular ECA antibody, angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 antibody|
|Cellular Localization||Angiotensin-converting enzyme , soluble form: Secreted , Cell membrane |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human ACE. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Human, Rat, Pig, Rabbit, Chimpanzee, Bovine|
|Predict Reactivity Note||Human (100%), Rat (80%), Pig (83%), Rabbit (87%), Chimpanzee (99%), Bovine (82%)|