|Full Name||angiotensin I converting enzyme|
|Product Description||Rabbit Polyclonal antibody to ACE (angiotensin I converting enzyme)|
|Background||This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes - the somatic form and the testicular form that are equally active. Multiple additional alternatively spliced variants have been identified but their full length nature has not been determined. [provided by RefSeq]|
|Synonyms||CD143 Antibody , DCP1 Antibody , angiotensin I converting enzyme Antibody , ACE1 Antibody , DCP Antibody , ICH Antibody , MVCD3 Antibody|
|Cellular Localization||Angiotensin-converting enzyme , soluble form: Secreted , Cell membrane |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human ACE. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Human (100%), Chimpanzee (98%)|