ACP2 antibody [N2C3]
|Applications||ICC/IF, IHC-P, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||48 kDa (note)
|Positive Controls||A431 , H1299 , HeLa , HepG2 , *H3347 , *CX-1 , *SW48 , *HCT116 , *Human Lymphoma Tissue|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||acid phosphatase 2, lysosomal|
|Product Description||Rabbit Polyclonal antibody to ACP2 (acid phosphatase 2, lysosomal)|
|Background||This gene encodes the beta subunit of lysosomal acid phosphatase (LAP). LAP is chemically and genetically distinct from red cell acid phosphatase. The encoded protein belongs to a family of distinct isoenzymes which hydrolyze orthophosphoric monoesters to alcohol and phosphate. Mutations in this gene or in the related alpha subunit gene cause acid phosphatase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq]|
|Synonyms||ACP2 antibody, LAP antibody, lysosomal acid phosphatase antibody, "acid phosphatase 2, lysosomal antibody"|
|Cellular Localization||Lysosome membrane; Single-pass membrane protein; Lumenal side , Lysosome lumen |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human ACP2. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Pig, Chimpanzee, Bovine|
|Predict Reactivity Note||Mouse (87%), Rat (87%), Pig (94%), Chimpanzee (100%), Bovine (94%)|