|Full Name||ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)|
|Product Description||Rabbit Polyclonal antibody to ACTR1A (ARP1 actin-related protein 1 homolog A, centractin alpha (yeast))|
|Background||This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60% identical at the amino acid level to conventional actin. [provided by RefSeq]|
|Synonyms||ARP1 antibody, CTRN1 antibody, FLJ52695 antibody, FLJ52800 antibody, FLJ55002 antibody, ACTR1A antibody, centrosome-associated actin homolog antibody, centractin antibody, actin-RPV antibody, alpha-centractin antibody, "ARP1 actin-related protein 1 homolog A, centractin alpha (yeast) antibody"|
|Cellular Localization||Cytoplasm , cytoskeleton , Centrosome |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human ACTR1A. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Dog, Chicken, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Rat (100%), Dog (100%), Chicken (98%), Rhesus Monkey (100%), Bovine (100%)|