|Full Name||activin A receptor type II-like 1|
|Product Description||Rabbit polyclonal antibody to ACVRL1 (activin A receptor type II-like 1)|
|Background||This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2. [provided by RefSeq]|
|Synonyms||ACVRLK1 antibody, ALK-1 antibody, ALK1 antibody, HHT antibody, HHT2 antibody, ORW2 antibody, SKR3 antibody, TSR-I antibody, ACVRL1 antibody, TGF-B superfamily receptor type I antibody, serine/threonine-protein kinase receptor R3 antibody, activin receptor-like kinase 1 antibody, "activin A receptor, type II-like kinase 1 antibody", activin A receptor type II-like 1 antibody|
|Cellular Localization||Membrane |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human ACVRL1. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Zebrafish, Bovine|
|Predict Reactivity Note||Rat (97%), Zebrafish (87%), Bovine (99%)|