|Full Name||cholinergic receptor, nicotinic, alpha 3|
|Product Description||Rabbit Polyclonal antibody to AChR alpha 3|
|Background||This locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described. [provided by RefSeq]|
|Synonyms||LNCR2 antibody, MGC104879 antibody, NACHRA3 antibody, PAOD2 antibody, CHRNA3 antibody, "neuronal nicotinic acetylcholine receptor, alpha3 subunit antibody", neuronal acetylcholine receptor subunit alpha-3 antibody, "cholinergic receptor, nicotinic, alpha polypeptide 3 antibody", "cholinergic receptor, nicotinic, alpha 3 antibody"|
|Cellular Localization||Cell junction , synapse , postsynaptic cell membrane , Cell membrane |
|Target||AChR alpha 3|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Nicotinic Acetylcholine Receptor alpha 3. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Chicken, Bovine|
|Predict Reactivity Note||Mouse (94%), Rat (94%), Chicken (87%), Bovine (96%)|