AChR alpha 6 antibody
|Applications||ELISA, FACS, ICC/IF, IHC-F, IHC-P, WB|
|Application Note||WB(1:100-500), ELISA(1:500-1000), IHC-P(1:100-500), IHC-F(1:100-500), FACS(1:100-500), IF(1:100-500)|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by Protein A and peptide affinity chromatography.|
|Full Name||cholinergic receptor, nicotinic, alpha 6 (neuronal)|
|Product Description||Rabbit Polyclonal antibody to AChR alpha 6|
|Background||This gene encodes an alpha subunit of neuronal nicotinic acetylcholine receptors. These receptors consist of five subunits and function as ion channels involved in neurotransmission. The encoded protein is a subunit of neuronal nicotinic acetylcholine receptors that mediate dopaminergic neurotransmission and are activated by acetylcholine and exogenous nicotine. Alternatively spliced transcript variants have been observed for this gene. Single nucleotide polymorphisms in this gene have been associated with both nicotine and alcohol dependence. [provided by RefSeq, Dec 2010]|
|Synonyms||CHNRA6 Antibody, cholinergic receptor, nicotinic, alpha 6 (neuronal) Antibody|
|Target||AChR alpha 6|
|Immunogen||The immunogen used to produce this antibody falls within the range 110-160a.a of human CHRNA6.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.