|Full Name||cholinergic receptor, nicotinic, beta 2 (neuronal)|
|Product Description||Rabbit Polyclonal antibody to AChR beta 2|
|Background||Neuronal acetylcholine receptors are homo- or heteropentameric complexes composed of homologous alpha and beta subunits. They belong to a superfamily of ligand-gated ion channels which allow the flow of sodium and potassium across the plasma membrane in response to ligands such as acetylcholine and nicotine. This gene encodes one of several beta subunits. Mutations in this gene are associated with autosomal dominant nocturnal frontal lobe epilepsy. [provided by RefSeq]|
|Synonyms||EFNL3 antibody, nAChRB2 antibody, CHRNB2 antibody, "cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal) antibody", neuronal acetylcholine receptor subunit beta-2 antibody, neuronal nicotinic acetylcholine receptor beta 2 antibody, "cholinergic receptor, nicotinic, beta 2 (neuronal) antibody"|
|Cellular Localization||Cell junction , synapse , postsynaptic cell membrane , Cell membrane |
|Target||AChR beta 2|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Nicotinic Acetylcholine Receptor beta 2. The exact sequence is proprietary.|
|Species Reactivity||Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Human, Chicken, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Human (100%), Chicken (98%), Rhesus Monkey (99%), Bovine (98%)|