|Full Name||cholinergic receptor, nicotinic, beta 1 (muscle)|
|Product Description||Rabbit Polyclonal antibody to AChR beta|
|Background||The muscle acetylcholine receptor is composed of five subunits: two alpha subunits and one beta, one gamma, and one delta subunit. This gene encodes the beta subunit of the acetylcholine receptor. The acetylcholine receptor changes conformation upon acetylcholine binding leading to the opening of an ion-conducting channel across the plasma membrane. Mutations in this gene are associated with slow-channel congenital myasthenic syndrome. [provided by RefSeq]|
|Synonyms||ACHRB antibody, CHRNB antibody, CMS1D antibody, CMS2A antibody, FLJ57107 antibody, SCCMS antibody, CHRNB1 antibody, acetylcholine receptor subunit beta antibody, "cholinergic receptor, nicotinic, beta polypeptide 1 (muscle) antibody", "cholinergic receptor, nicotinic, beta 1 (muscle) antibody"|
|Cellular Localization||Cell junction , synapse , postsynaptic cell membrane , Cell membrane |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Nicotinic Acetylcholine Receptor beta. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Bovine|
|Predict Reactivity Note||Mouse (88%), Rat (87%), Bovine (93%)|