|Full Name||cholinergic receptor, nicotinic, gamma|
|Product Description||Rabbit Polyclonal antibody to AChR gamma (cholinergic receptor, nicotinic, gamma)|
|Background||For background information on the acetylcholine receptor (AChR), see CHRNA1 (MIM 100690). Two forms of AChR are found in mammalian skeletal muscle cells. The mature form is predominant in innervated adult muscle and the embryonic form is present in fetal and denervated muscle. Embryonic and mature AChR differ by the replacement of the gamma subunit in the pentameric glycoprotein complex by its isoform, the epsilon subunit (MIM 100725), which is specific to the mature AChR subtype. This switch is mediated by ARIA (acetylcholine receptor-inducing activity; MIM 142445).[supplied by OMIM]|
|Synonyms||ACHRG antibody, MGC133376 antibody, CHRNG antibody, acetylcholine receptor subunit gamma antibody, "acetylcholine receptor, muscle, gamma subunit antibody", "cholinergic receptor, nicotinic, gamma polypeptide antibody", "cholinergic receptor, nicotinic, gamma antibody"|
|Cellular Localization||Cell junction , synapse , postsynaptic cell membrane , Cell membrane |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human AChR gamma. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Bovine|
|Predict Reactivity Note||Mouse (83%), Rat (83%), Bovine (89%)|