| Full Name | ADAM metallopeptidase domain 17 |
| Product Description | Rabbit Polyclonal antibody to ADAM17 |
| Background | This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme; binds mitotic arrest deficient 2 protein; and also plays a prominent role in the activation of the Notch signaling pathway. [provided by RefSeq, Jul 2008] |
| Synonyms | CSVP Antibody , ADAM metallopeptidase domain 17 Antibody , ADAM18 Antibody , TACE Antibody , NISBD Antibody , CD156B Antibody |
| Specificity | 80 to 130 kDa bands can be detected, which may represent mature protein, precursor, and glycosylated TACE. |
| Host | Rabbit |
| Clonality | Polyclonal |
| Target | ADAM17 |
| Isotype | IgG |
| Immunogen | TACE antibody was raised against a peptide corresponding to 17 amino acids near the carboxy terminus of human TACE. |
| Antigen Species | Human |
| Species Reactivity | Human |
| Conjugation | Unconjugated |