Not tested in other applications.
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||91 kDa (note)
|Positive Controls||293T , A431 , HeLa , HepG2 , Neuro 2A , C8D30 , NIH-3T3 , Raw264.7 , C2C12|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||ADAM metallopeptidase domain 9|
|Product Description||Rabbit Polyclonal antibody to ADAM9 (ADAM metallopeptidase domain 9)|
|Background||This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene interacts with SH3 domain-containing proteins, binds mitotic arrest deficient 2 beta protein, and is also involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor. Two alternative splice variants have been identified, encoding distinct isoforms. [provided by RefSeq]|
|Synonyms||MCMP Antibody , MDC9 Antibody , CORD9 Antibody , Mltng Antibody , ADAM metallopeptidase domain 9 Antibody|
|Cellular Localization||Isoform 1: Cell membrane , Isoform 2: Secreted |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human ADAM9. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Dog, Chicken, Bovine|
|Predict Reactivity Note||Rat (92%), Dog (93%), Chicken (80%), Bovine (88%)|