|Full Name||ADAM metallopeptidase with thrombospondin type 1 motif, 5|
|Product Description||Rabbit Polyclonal antibody to ADAMTS5 (A disintegrin and metalloproteinase with thrombospondin motifs 5)|
|Background||This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains two C-terminal TS motifs and functions as aggrecanase to cleave aggrecan, a major proteoglycan of cartilage. [provided by RefSeq]|
|Synonyms||ADAMTS11 antibody, ADMP-2 antibody, FLJ36738 antibody, ADAMTS5 antibody, a disintegrin and metalloproteinase with thrombospondin motifs 11 antibody, A disintegrin and metalloproteinase with thrombospondin motifs 5 antibody, "a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2) antibody", aggrecanase-2 antibody, "ADAM metallopeptidase with thrombospondin type 1 motif, 5 antibody"|
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human ADAMTS5. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Rat (100%), Bovine (100%)|