|Full Name||adenylosuccinate lyase|
|Product Description||Rabbit Polyclonal antibody to ADSL (adenylosuccinate lyase)|
|Background||Adenylsuccinate lyase is involved in both de novo synthesis of purines and formation of adenosine monophosphate from inosine monophosphate. It catalyzes two reactions in AMP biosynthesis: the removal of a fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to give aminoimidazole carboxamide ribotide (AICA) and removal of fumarate from adenylosuccinate to give AMP. Adenylosuccinase deficiency results in succinylpurinemic autism, psychomotor retardation, and , in some cases, growth retardation associated with muscle wasting and epilepsy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]|
|Synonyms||AMPS antibody, ASASE antibody, ASL antibody, ADSL antibody, adenylosuccinate lyase antibody, adenylosuccinase antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human ADSL. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Zebrafish, Xenopus laevis, Pig, Chicken, Chimpanzee, Bovine|
|Predict Reactivity Note||Rat (95%), Zebrafish (84%), Xenopus laevis (90%), Pig (97%), Chicken (91%), Chimpanzee (98%), Bovine (95%)|