|Full Name||aminoacyl tRNA synthetase complex-interacting multifunctional protein 1|
|Product Description||Rabbit Polyclonal antibody to AIMP1 (aminoacyl tRNA synthetase complex-interacting multifunctional protein 1)|
|Background||The protein encoded by this gene is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor protein is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex, and it modulates aminoacylation activity of tRNA synthetase in normal cells. This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene has been identified on chromosome 20. [provided by RefSeq]|
|Synonyms||EMAP2 antibody, EMAPII antibody, SCYE1 antibody, p43 antibody, AIMP1 antibody, "small inducible cytokine subfamily E, member 1 (endothelial monocyte-activating) antibody", endothelial-monocyte activating polypeptide II antibody, aminoacyl tRNA synthase complex-interacting multifunctional protein 1 antibody, endothelial monocyte-activating polypeptide 2 antibody, ARS-interacting multifunctional protein 1 antibody, multisynthetase complex auxiliary component p43 antibody, multisynthase complex auxiliary component p43 antibody, aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 antibody|
|Cellular Localization||Nucleus , Cytoplasm , cytosol , Cytoplasmic vesicle , secretory vesicle , Secreted , Endoplasmic reticulum , Golgi apparatus |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human AIMP1. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Zebrafish, Xenopus laevis, Pig, Bovine|
|Predict Reactivity Note||Rat (97%), Zebrafish (83%), Xenopus laevis (85%), Pig (94%), Bovine (94%)|