|Full Name||A kinase (PRKA) anchor protein 10|
|Product Description||Rabbit Polyclonal antibody to AKAP10 (A kinase (PRKA) anchor protein 10)|
|Background||The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein interacts with both the type I and type II regulatory subunits of PKA; therefore, it is a dual-specific AKAP. This protein is highly enriched in mitochondria. It contains RGS (regulator of G protein signalling) domains, in addition to a PKA-RII subunit-binding domain. The mitochondrial localization and the presence of RGS domains may have important implications for the function of this protein in PKA and G protein signal transduction. [provided by RefSeq]|
|Synonyms||D-AKAP2 antibody, MGC9414 antibody, PRKA10 antibody, AKAP10 antibody, dual specificity A kinase-anchoring protein 2 antibody, D-AKAP-2 antibody, a kinase anchor protein 10, mitochondrial antibody, A-kinase anchor protein 10, mitochondrial antibody, dual-specificity A-kinase anchoring protein 2 antibody, protein kinase A anchoring protein 10 antibody, protein kinase A-anchoring protein 10 antibody, AKAP-10 antibody, mitochondrial A kinase PPKA anchor protein 10 antibody, A kinase (PRKA) anchor protein 10 antibody|
|Cellular Localization||Mitochondrion , Membrane , Cytoplasm|
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human AKAP10. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Mouse (85%), Rat (85%)|