AKR1B1 antibody [N1C3]
|Applications||ICC/IF, IHC-P, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||36 kDa (note)
|Positive Controls||293T , A431 , HeLa , HepG2 , Molt-4 , Raji|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||aldo-keto reductase family 1, member B1 (aldose reductase)|
|Product Description||Rabbit Polyclonal antibody to AKR1B1 (aldo-keto reductase family 1, member B1 (aldose reductase))|
|Background||This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for this gene. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database. [provided by RefSeq]|
|Synonyms||ADR antibody, ALDR1 antibody, ALR2 antibody, AR antibody, MGC1804 antibody, AKR1B1 antibody, aldehyde reductase 1 antibody, aldose reductase antibody, aldo-keto reductase family 1 member B1 antibody, low Km aldose reductase antibody, Lii5-2 CTCL tumor antigen antibody, "aldo-keto reductase family 1, member B1 (aldose reductase) antibody"|
|Cellular Localization||Cytoplasm |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human AKR1B1. The exact sequence is proprietary.|
|Species Reactivity||Human, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Dog, Pig, Rabbit, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Dog (91%), Pig (86%), Rabbit (89%), Rhesus Monkey (98%), Bovine (87%)|