|Full Name||v-akt murine thymoma viral oncogene homolog 3|
|Product Description||Rabbit Polyclonal antibody to AKT3 (E17K Mutant Specific) (v-akt murine thymoma viral oncogene homolog 3)|
|Background||The protein encoded by this gene is a member of the AKT, also called PKB, serine/threonine protein kinase family. AKT kinases are known to be regulators of cell signaling in response to insulin and growth factors. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake. This kinase has been shown to be stimulated by platelet-derived growth factor (PDGF), insulin, and insulin-like growth factor 1 (IGF1). Alternatively splice transcript variants encoding distinct isoforms have been described. [provided by RefSeq]|
|Cellular Localization||Cytoplasm , Membrane|
|Target||AKT3 (E17K Mutant Specific)|
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of Human AKT3 (E17K Mutant Specific). The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Pig, Rhesus Monkey, Chimpanzee, Bovine|
|Predict Reactivity Note||Mouse (100%), Rat (100%), Pig (100%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (100%)|