|Full Name||aminolevulinate, delta-, synthase 2|
|Product Description||Rabbit Polyclonal antibody to ALAS-E (aminolevulinate, delta-, synthase 2)|
|Background||The product of this gene specifies an erythroid-specific mitochondrially located enzyme. The encoded protein catalyzes the first step in the heme biosynthetic pathway. Defects in this gene cause X-linked pyridoxine-responsive sideroblastic anemia. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]|
|Synonyms||ALAS-E antibody, ALASE antibody, ANH1 antibody, ASB antibody, FLJ93603 antibody, XLDPP antibody, XLSA antibody, ALAS2 antibody, 5-aminolevulinic acid synthase 2 antibody, delta-ALA synthetase antibody, "5-aminolevulinate synthase, erythroid-specific, mitochondrial antibody", delta-aminolevulinate synthase 2 antibody, delta-ALA synthase 2 antibody, "aminolevulinate, delta-, synthase 2 antibody"|
|Cellular Localization||Mitochondrion matrix |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human ALAS-E. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Zebrafish, Xenopus laevis, Bovine|
|Predict Reactivity Note||Rat (95%), Zebrafish (80%), Xenopus laevis (81%), Bovine (95%)|