|Full Name||aldehyde dehydrogenase 1 family, member A1|
|Product Description||Rabbit Polyclonal antibody to ALDH1A1 (retinal dehydrogenase 1)|
|Background||This protein belongs to the aldehyde dehydrogenases family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of the mitochondrial isozyme. This gene encodes a cytosolic isoform, which has a high affinity for aldehydes. [provided by RefSeq]|
|Synonyms||ALDC antibody, ALDH-E1 antibody, ALDH1 antibody, ALDH11 antibody, MGC2318 antibody, PUMB1 antibody, RALDH1 antibody, ALDH1A1 antibody, ALHDII antibody, ALDH class 1 antibody, retinaldehyde dehydrogenase 1 antibody, acetaldehyde dehydrogenase 1 antibody, "aldehyde dehydrogenase 1, soluble antibody", RALDH 1 antibody, "aldehyde dehydrogenase, liver cytosolic antibody", retinal dehydrogenase 1 antibody, "aldehyde dehydrogenase 1 family, member A1 antibody"|
|Cellular Localization||Cytoplasm |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human ALDH1A1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Dog, Rabbit, Chicken, Sheep, Chimpanzee, Bovine|
|Predict Reactivity Note||Mouse (85%), Rat (84%), Dog (88%), Rabbit (88%), Chicken (81%), Sheep (92%), Chimpanzee (100%), Bovine (90%)|