| Full Name | aldehyde dehydrogenase 1 family, member A2 |
| Background | This protein belongs to the aldehyde dehydrogenase family of proteins. The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida. Three transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq] |
| Synonyms | MGC26444 antibody, RALDH(II) antibody, RALDH2 antibody, RALDH2-T antibody, ALDH1A2 antibody, retinal dehydrogenase 2 antibody, retinaldehyde-specific dehydrogenase type 2 antibody, RALDH 2 antibody, "aldehyde dehydrogenase 1 family, member A2 antibody" |
| Cellular Localization | Cytoplasm |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human ALDH1A2. The exact sequence is proprietary. |
| Antigen Species | Human |
| Species Reactivity | Human, Mouse, Rat |
Predicted Cross Reactivity species  Predicted cross-reactivity:
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
| Rat, Zebrafish, Japanese Medaka, Xenopus laevis, Dog, Chicken |
| Predict Reactivity Note | Rat (96%), Zebrafish (81%), Japanese Medaka (81%), Xenopus laevis (88%), Dog (99%), Chicken (95%) |
| Conjugation | Unconjugated |