ALDH5A1 antibody [N1C1]
|Applications||ICC/IF, IHC-P, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||57 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji , mouse brain , *A549 |
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||aldehyde dehydrogenase 5 family, member A1|
|Product Description||Rabbit Polyclonal antibody to ALDH5A1 (aldehyde dehydrogenase 5 family, member A1)|
|Background||This protein belongs to the aldehyde dehydrogenase family of proteins. This gene encodes a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, is a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA). In response to the defect, physiologic fluids from patients accumulate GHB, a compound with numerous neuromodulatory properties. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq]|
|Synonyms||SSADH antibody, SSDH antibody, ALDH5A1 antibody, "succinate-semialdehyde dehydrogenase, mitochondrial antibody", aldehyde dehydrogenase family 5 member A1 antibody, mitochondrial succinate semialdehyde dehydrogenase antibody, NAD(+)-dependent succinic semialdehyde dehydrogenase antibody, "aldehyde dehydrogenase 5 family, member A1 antibody"|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human ALDH5A1. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Pig, Chimpanzee, Bovine|
|Predict Reactivity Note||Rat (84%), Pig (85%), Chimpanzee (92%), Bovine (86%)|