| Full Name | aldehyde dehydrogenase 6 family, member A1 |
| Background | This protein belongs to the aldehyde dehydrogenases family of proteins. This enzyme plays a role in the valine and pyrimidine catabolic pathways. The product of this gene, a mitochondrial methylmalonate semialdehyde dehydrogenase, catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids. [provided by RefSeq] |
| Synonyms | MGC40271 antibody, MMSADHA antibody, MMSDH antibody, ALDH6A1 antibody, mitochondrial acylating methylmalonate-semialdehyde dehydrogenase antibody, methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial antibody, aldehyde dehydrogenase family 6 member A1 antibody, malonate-semialdehyde dehydrogenase antibody, aldehyde dehydrogenase 6 family, member A1 antibody |
| Cellular Localization | Mitochondrion |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human ALDH6A1. The exact sequence is proprietary. |
| Antigen Species | Human |
| Species Reactivity | Human, Mouse |
Predicted Cross Reactivity species  Predicted cross-reactivity:
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
| Rat, Zebrafish, Xenopus laevis, Bovine |
| Predict Reactivity Note | Rat (96%), Zebrafish (86%), Xenopus laevis (86%), Bovine (96%) |
| Conjugation | Unconjugated |