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1 .GTX55395 ALK (phospho Tyr1507) antibody

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ALK (phospho Tyr1507) antibody


  • Host / ClonalityRabbit Polyclonal
  • ApplicationsWB
  • Species reactivityHuman, Mouse
Cat No: GTX55395
Package Price Qty
100 ulUSD 319.00
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  • Anti-ALK (phospho Tyr1507) antibody used in Western Blot (WB). GTX55395
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  • Datasheet
  • Application Information: ALK (phospho Tyr1507) antibody

Catalog Number GTX55395
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Product Name ALK (phospho Tyr1507) antibody
See all ALK products
ApplicationsWB
Application NoteWB: 1:500 - 1:1000
Form SuppliedLiquid
Concentration1 mg/ml (Please refer to the vial label for the specific concentration)
PurificationAntibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

  • Specifications: ALK (phospho Tyr1507) antibody

Full Nameanaplastic lymphoma receptor tyrosine kinase
BackgroundThis gene encodes a receptor tyrosine kinase, which belongs to the insulin receptor superfamily. This protein comprises an extracellular domain, an hydrophobic stretch corresponding to a single pass transmembrane region, and an intracellular kinase domain. It plays an important role in the development of the brain and exerts its effects on specific neurons in the nervous system. This gene has been found to be rearranged, mutated, or amplified in a series of tumours including anaplastic large cell lymphomas, neuroblastoma, and non-small cell lung cancer. The chromosomal rearrangements are the most common genetic alterations in this gene, which result in creation of multiple fusion genes in tumourigenesis, including ALK (chromosome 2)/EML4 (chromosome 2), ALK/RANBP2 (chromosome 2), ALK/ATIC (chromosome 2), ALK/TFG (chromosome 3), ALK/NPM1 (chromosome 5), ALK/SQSTM1 (chromosome 5), ALK/KIF5B (chromosome 10), ALK/CLTC (chromosome 17), ALK/TPM4 (chromosome 19), and ALK/MSN (chromosome X).[provided by RefSeq, Jan 2011]
SynonymsCD246 Antibody , anaplastic lymphoma receptor tyrosine kinase Antibody , NBLST3 Antibody , ALK Antibody
SpecificityThe antibody detects endogenous level of ALK only when phosphorylated at tyrosine 1507.
HostRabbit
ClonalityPolyclonal
IsotypeIgG
ImmunogenPeptide sequence around phosphorylation site of Tyrosine 1507 (P-T-Y(p)-G-S) derived from Human ALK.
Antigen SpeciesHuman
Species ReactivityHuman, Mouse
ConjugationUnconjugated

  • Storage Conditions: ALK (phospho Tyr1507) antibody

Storage BufferRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage InstructionStore at -20˚C/1 year
NotesFor In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
ResearchArea
  • Cancer > Type of cancer > Lung > Non-small cell
  • Immunology > CD marker
  • Stem Cell Development > Development > Ectoderm > Nervous system development
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ALK (phospho Tyr1507) antibody validated data
  • Anti-ALK (phospho Tyr1507) antibody used in Western Blot (WB). GTX55395
    • GTX55395 WB Image
      Western blot analysis of extracts from COS7 cells treated with Anisomycin using Phospho-ALK (Tyr1507) antibody. The lane on the right is treated with the antigen-specific peptide.
      Top
  • Anti-ALK (phospho Tyr1507) antibody used in Western Blot (WB). GTX55395
    • GTX55395 WB Image
      Western blot analysis of extracts from COS7 cells treated with Anisomycin using Phospho-ALK (Tyr1507) antibody. The lane on the right is treated with the antigen-specific peptide.
      Top
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