|Full Name||STE20-related kinase adaptor beta|
|Product Description||Rabbit Polyclonal antibody to ALS2CR2 (STE20-related kinase adaptor beta)|
|Background||This gene encodes a protein that belongs to the serine/threonine protein kinase STE20 subfamily. One of the active site residues in the protein kinase domain of this protein is altered, and it is thus a pseudokinase. This protein is a component of a complex involved in the activation of serine/threonine kinase 11, a master kinase that regulates cell polarity and energy-generating metabolism. This complex regulates the relocation of this kinase from the nucleus to the cytoplasm, and it is essential for G1 cell cycle arrest mediated by this kinase. The protein encoded by this gene can also interact with the X chromosome-linked inhibitor of apoptosis protein, and this interaction enhances the anti-apoptotic activity of this protein via the JNK1 signal transduction pathway. Two pseudogenes, located on chromosomes 1 and 7, have been found for this gene. [provided by RefSeq]|
|Synonyms||ALS2CR2 antibody, CALS-21 antibody, ILPIP antibody, ILPIPA antibody, MGC102916 antibody, PAPK antibody, STRADB antibody, pseudokinase ALS2CR2 antibody, "amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 2 antibody", STRAD beta antibody, ILP-interacting protein ILPIPA antibody, amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein antibody, STE20-related kinase adapter protein beta antibody, STE20-related kinase adaptor beta antibody|
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human ALS2CR2. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Rhesus Monkey (100%)|