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1 .GTX15894 AMCR antibody

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AMCR antibody


  • Host / ClonalityRabbit Polyclonal
  • ApplicationsIHC, IM, WB
  • Species reactivityHuman, Mouse
Cat No: GTX15894
Package Price Qty
100 μgUSD 359.00
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  • Datasheet
  • Application Information: AMCR antibody

Catalog Number GTX15894
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Product Name AMCR antibody
See all AMACR products
ApplicationsIHC, IM, WB
Application NoteIHC: Use at a dilution of 1/100. IM: Use at an assay dependent dilution. WB: Use at a dilution of 1/500. Predicted molecular weight: 42 kDa corresponding to variant AMCR I. Optimal dilutions/concentrations should be determined by the end user.
Concentration0.75 mg/ml (Please refer to the vial label for the specific concentration)
PurificationImmunogen affinity purified
Purification NoteAffinity purified against immobilized antigen. Supplied as a pure IgG fraction.

  • Specifications: AMCR antibody

Full Namealpha-methylacyl-CoA racemase
BackgroundAlpha-methyacyl-CoA racemase (AMCR), is an enzyme invloved in beta oxidation of branched chain fatty acids and bile salt intermediates, and has recently been identified as a neomarker for prostate cancer, where it is over expressed. Several different isoforms have been reported that are produced either by extensinve alternatve splicing of 5 exons or by use of alternate initiation codons. At least 2 different transcripts, each derived from the 5 exons, have been reported, AMCR I and AMCR II. AMCR I is the most abundant form and enclodes for a 382 amino acid protein (42kDa). The other isoform AMCR II exhibits significnat homolgy to fumerate hydratase and encoes a 288 amino acid protein (32 kDa). Several other variants of IA and IIA isoforms are charcterized recently. The variants lack exon 3 and are designated as IB and IIB. In prostate tumor tissues that over express AMCR, both the A and B forms are over-expressed.
SynonymsAMACR, AMCR, 604489, 23600, RACE, Q9UHK6
Cellular LocalizationMitochondrial
SpecificityGTX15894 is specific for AMCR I
HostRabbit
ClonalityPolyclonal
IsotypeIgG
ImmunogenSynthetic peptide: TDACVTPVLT FEEWHHD(C), corresponding to C Terminal amino acids 290-307 of Human AMCR, the peptide was modified post-synthesis.
Antigen SpeciesHuman
Species ReactivityHuman, Mouse
ConjugationUnconjugated

  • Storage Conditions: AMCR antibody

Storage BufferPreservative: NoneConstituents: BSA
Storage InstructionKeep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.
NotesFor In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
ResearchArea
  • Cancer > Tumor biomarkers
  • Cancer > Type of cancer > Colorectal > Colon
  • Cancer > Type of cancer > Lung > Other
  • Cancer > Type of cancer > Prostate cancer
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AMCR antibody validated data
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All products are for research use only—Not for use in diagnostic procedures.