|Full Name||protein kinase, AMP-activated, gamma 1 non-catalytic subunit|
|Product Description||Rabbit Polyclonal antibody to AMPK gamma 1 (5'-AMP-activated protein kinase subunit gamma-1)|
|Background||The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq]|
|Synonyms||AMPKG antibody, MGC8666 antibody, PRKAG1 antibody, AMPK gamma1 antibody, "5'-AMP-activated protein kinase, gamma-1 subunit antibody", AMPK gamma-1 chain antibody, 5'-AMP-activated protein kinase subunit gamma-1 antibody, "protein kinase, AMP-activated, gamma 1 non-catalytic subunit antibody"|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human AMPK gamma 1. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Zebrafish, Xenopus laevis, Pig, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Rat (98%), Zebrafish (86%), Xenopus laevis (80%), Pig (100%), Rhesus Monkey (100%), Bovine (100%)|