|Full Name||protein kinase, AMP-activated, gamma 3 non-catalytic subunit|
|Product Description||Rabbit Polyclonal antibody to AMPK gamma 3|
|Background||The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. It is dominantly expressed in skeletal muscle. Studies of the pig counterpart suggest that this subunit may play a key role in the regulation of energy metabolism in skeletal muscle. [provided by RefSeq, Jul 2008]|
|Synonyms||PRKAG3 Antibody, AMPKG3 Antibody, protein kinase, AMP-activated, gamma 3 non-catalytic subunit Antibody|
|Specificity||AMPK gamma 3/PRKAG3|
|Target||AMPK gamma 3|
|Immunogen||KLH conjugated synthetic peptide derived from human AMPK gamma 3|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Bovine, Rabbit, Horse, Sheep, Pig|