|Full Name||angiopoietin-like 3|
|Product Description||Rabbit Polyclonal antibody to ANGPTL3 (angiopoietin-like 3)|
|Background||The protein encoded by this gene is a member of the angiopoietin-like family of secreted factors. It is predominantly expressed in the liver, and has the characteristic structure of angiopoietins, consisting of a signal peptide, N-terminal coiled-coil domain and the C-terminal fibrinogen (FBN)-like domain. The FBN-like domain in angiopoietin-like 3 protein was shown to bind alpha-5/beta-3 integrins, and this binding induced endothelial cell adhesion and migration. This protein may also play a role in the regulation of angiogenesis. [provided by RefSeq]|
|Synonyms||ANGPT5 antibody, FHBL2 antibody, ANGPTL3 antibody, ANG-5 antibody, angiopoietin-related protein 3 antibody, angiopoietin 5 antibody, angiopoietin-like 3 antibody|
|Cellular Localization||Secreted |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human ANGPTL3. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Pig, Bovine|
|Predict Reactivity Note||Mouse (80%), Pig (85%), Bovine (86%)|