|Full Name||amine oxidase, copper containing 2 (retina-specific)|
|Product Description||Rabbit Polyclonal antibody to AOC2 (amine oxidase, copper containing 2 (retina-specific))|
|Background||Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes and ammonia in the presence of copper and quinone cofactor. This gene shows high sequence similarity to copper amine oxidases from various species ranging from bacteria to mammals. The protein contains several conserved motifs including the active site of amine oxidases and the histidine residues that likely bind copper. It may be a critical modulator of signal transmission in retina, possibly by degrading the biogenic amines dopamine, histamine, and putrescine. This gene may be a candidate gene for hereditary ocular diseases. Alternate splicing results in multiple transcript variants. [provided by RefSeq]|
|Synonyms||RAO Antibody, amine oxidase, copper containing 2 (retina-specific) Antibody, DAO2 Antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human AOC2. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Bovine (92%)|