|Full Name||transcription factor AP-2 beta (activating enhancer binding protein 2 beta)|
|Product Description||Rabbit Polyclonal antibody to AP2 beta (transcription factor AP-2 beta (activating enhancer binding protein 2 beta))|
|Background||This gene encodes a member of the AP-2 family of transcription factors. AP-2 proteins form homo- or hetero-dimers with other AP-2 family members and bind specific DNA sequences. They are thought to stimulate cell proliferation and suppress terminal differentiation of specific cell types during embryonic development. Specific AP-2 family members differ in their expression patterns and binding affinity for different promoters. This protein functions as both a transcriptional activator and repressor. Mutations in this gene result in autosomal dominant Char syndrome, suggesting that this gene functions in the differentiation of neural crest cell derivatives. [provided by RefSeq]|
|Synonyms||AP-2B antibody, AP2-B antibody, MGC21381 antibody, TFAP2B antibody, transcription factor AP-2-beta antibody, activating enhancer-binding protein 2-beta antibody, activating enhancer binding protein 2 beta antibody, AP2-beta antibody, transcription factor AP-2 beta (activating enhancer binding protein 2 beta) antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human AP2 beta. The exact sequence is proprietary.|
|Species Reactivity||Human, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Zebrafish, Xenopus laevis, Dog, Pig, Chicken, Bovine|
|Predict Reactivity Note||Mouse (100%), Zebrafish (94%), Xenopus laevis (99%), Dog (100%), Pig (99%), Chicken (99%), Bovine (100%)|