|Full Name||adaptor-related protein complex 2, mu 1 subunit|
|Product Description||Rabbit Polyclonal antibody to AP2M1 (adaptor-related protein complex 2, mu 1 subunit)|
|Background||This gene encodes a subunit of the heterotetrameric coat assembly protein complex 2 (AP2), which belongs to the adaptor complexes medium subunits family. The encoded protein is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. The encoded protein may also play an important role in regulating the intracellular trafficking and function of CTLA-4 protein. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]|
|Synonyms||AP50 antibody, CLAPM1 antibody, mu2 antibody, AP2M1 antibody, "clathrin-associated/assembly/adaptor protein, medium 1 antibody", plasma membrane adaptor AP-2 50kDA protein antibody, AP-2 mu chain antibody, adaptor protein complex AP-2 subunit mu antibody, clathrin coat adaptor protein AP50 antibody, adapter-related protein complex 2 mu subunit antibody, plasma membrane adaptor AP-2 50 kDa protein antibody, clathrin coat-associated protein AP50 antibody, clathrin coat assembly protein AP50 antibody, AP-2 mu 2 chain antibody, AP-2 complex subunit mu antibody, "clathrin adaptor complex AP2, mu subunit antibody", adaptin-mu2 antibody, clathrin assembly protein complex 2 medium chain antibody, HA2 50 kDA subunit antibody, "adaptor-related protein complex 2, mu 1 subunit antibody"|
|Cellular Localization||Cell membrane , Membrane , coated pit |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human AP2M1. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Xenopus laevis, Dog, Pig, Chicken, Rhesus Monkey, Chimpanzee, Bovine|
|Predict Reactivity Note||Rat (100%), Xenopus laevis (98%), Dog (100%), Pig (98%), Chicken (98%), Rhesus Monkey (98%), Chimpanzee (99%), Bovine (100%)|