| Full Name | anaphase promoting complex subunit 10 |
| Product Description | Rabbit Polyclonal antibody to Apc10 |
| Background | Apc10 is a core subunit of the anaphase-promoting complex (APC), or cyclosome, a ubiquitin protein ligase that is essential for progression through the cell cycle. APC initiates sister chromatid separation by ubiquitinating the anaphase inhibitor securin (PTTG1; MIM 604147) and triggers exit from mitosis by ubiquitinating cyclin B (CCNB1; MIM 123836), the activating subunit of cyclin-dependent kinase-1 (CDK1; MIM 116940) (summary by Wendt et al., 2001 [PubMed 11524682]).[supplied by OMIM, Feb 2011] |
| Synonyms | DOC1 Antibody , anaphase promoting complex subunit 10 Antibody , ANAPC10 Antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Target | Apc10 |
| Isotype | IgG |
| Immunogen | Apc10 antibody was raised against a 16 amino acid synthetic peptide near the center of human Apc10. |
| Antigen Species | Human |
| Species Reactivity | Mouse |
| Conjugation | Unconjugated |