|Full Name||N-acylaminoacyl-peptide hydrolase|
|Product Description||Rabbit polyclonal antibody to APEH (N-acylaminoacyl-peptide hydrolase)|
|Background|| This gene encodes the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. This gene is located within the same region of chromosome 3 (3p21) as the aminoacylase gene, and deletions at this locus are also associated with a decrease in aminoacylase activity. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. It can play an important role in destroying oxidatively damaged proteins in living cells. Deletions of this gene locus are found in various types of carcinomas, including small cell lung carcinoma and renal cell carcinoma. [provided by RefSeq]|
|Synonyms||ACPH antibody, APH antibody, D3F15S2 antibody, D3S48E antibody, DNF15S2 antibody, MGC2178 antibody, OPH antibody, APEH antibody, oxidized protein hydrolase antibody, acyl-peptide hydrolase antibody, acylaminoacyl-peptidase antibody, acylamino-acid-releasing enzyme antibody, N-acylaminoacyl-peptide hydrolase antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human APEH. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Pig, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Mouse (88%), Rat (89%), Pig (89%), Rhesus Monkey (98%), Bovine (85%)|