|Full Name||anterior pharynx defective 1 homolog A (C. elegans)|
|Product Description||Goat polyclonal antibody to APH1A|
|Background||Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor for the presenilin homodimer that promotes the formation of a stable complex. |
|Synonyms||anterior pharynx defective 1 homolog A (C. elegans), APH-1A, CGI-78, anterior pharynx defective1 homolog A, CGI78, APH1A, anterior pharynx defective1 homolog A (C. elegans), 6530402N02Rik, anterior pharynx defective 1 homolog A, APH-1, APH 1, APH 1A, CGI 78, APH1|
|Cellular Localization||Predominantly located in the endoplasmic reticulum and in the cis-Golgi. |
|Specificity||This antibody is specific for APH1A.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Dog, Pig, Bovine|