|Full Name||adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1|
|Product Description||Goat polyclonal antibody to APPL1|
|Background||Required for the regulation of cell proliferation in response to extracellular signals from an early endosomal compartment. Links Rab5 to nuclear signal transduction. |
|Synonyms||APPL1, adaptor protein containing pH domain, PTB domain and leucine zipper motif, signaling adaptor protein DIP13alpha, DIP13alpha, APPL|
|Cellular Localization||Early endosomal membrane-bound and nuclear. Translocated into the nucleus upon release from endosomal membranes following internalization of EGF. |
|Specificity||This antibody is specific for APPL1.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Human, Mouse, Rat, Dog, Bovine|