|Full Name||adenine phosphoribosyltransferase|
|Product Description||Rabbit Polyclonal antibody to APRT (adenine phosphoribosyltransferase)|
|Background||Adenine phosphoribosyltransferase belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]|
|Synonyms||AMP antibody, DKFZp686D13177 antibody, MGC125856 antibody, MGC125857 antibody, MGC129961 antibody, APRT antibody, AMP pyrophosphorylase antibody, AMP diphosphorylase antibody, transphosphoribosidase antibody, adenine phosphoribosyltransferase antibody|
|Immunogen||Full length human APRT Recombinant protein.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Bovine|
|Predict Reactivity Note||Mouse (83%), Rat (85%), Bovine (85%)|