|Full Name||ADP-ribosylation factor GTPase activating protein 3|
|Product Description||Rabbit Polyclonal antibody to ARFGAP3 (ADP-ribosylation factor GTPase activating protein 3)|
|Background||The protein encoded by this gene is a GTPase-activating protein (GAP) that associates with the Golgi apparatus and regulates the early secretory pathway of proteins. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1 (ARF1)-bound GTP, which is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is a prerequisite for the fusion of these vesicles with target compartments. The activity of this protein is sensitive to phospholipids. Multiple transcript variants encoding different isoforms have been found for this gene. This gene was originally known as ARFGAP1, but that is now the name of a related but different gene. [provided by RefSeq]|
|Synonyms||ARFGAP1 antibody, FLJ45618 antibody, ARFGAP3 antibody, ARF GAP 3 antibody, ADP-ribosylation factor GTPase activating protein 1 antibody, ADP-ribosylation factor GTPase-activating protein 3 antibody, ADP-ribosylation factor GTPase activating protein 3 antibody|
|Cellular Localization||Cytoplasm , Golgi apparatus membrane |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human ARFGAP3. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rhesus Monkey, Chimpanzee, Bovine|
|Predict Reactivity Note||Rhesus Monkey (94%), Chimpanzee (97%), Bovine (84%)|