|Full Name||arginase, type II|
|Product Description||Rabbit Polyclonal antibody to ARG2 (arginase-2, mitochondrial)|
|Background|| Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exists (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type II isoform encoded by this gene, is located in the mitochondria and expressed in extra-hepatic tissues, especially kidney. The physiologic role of this isoform is poorly understood; it is thought to play a role in nitric oxide and polyamine metabolism. Transcript variants of the type II gene resulting from the use of alternative polyadenylation sites have been described. [provided by RefSeq]|
|Synonyms||ARG2 antibody, L-arginine ureahydrolase antibody, arginase 2 antibody, L-arginine amidinohydrolase antibody, non-hepatic arginase antibody, nonhepatic arginase antibody, kidney-type arginase antibody, type II arginase antibody, kidney arginase antibody, "arginase-2, mitochondrial antibody", "arginase, type II antibody"|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human ARG2. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Dog, Rabbit, Chicken, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Rat (87%), Dog (91%), Rabbit (88%), Chicken (81%), Rhesus Monkey (98%), Bovine (92%)|