| Full Name | mesencephalic astrocyte-derived neurotrophic factor |
| Background | The protein encoded by this gene is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and promotes cell proliferation. The protein was initially thought to be longer at the N-terminus and to contain an arginine-rich region but transcribed evidence indicates a smaller open reading frame that does not encode the arginine tract. The presence of a specific mutation changing the previously numbered codon 50 from ATG to AGG, or deletion of that codon, has been reported in a variety of solid tumors. With the protein size correction, this codon is now identified as the initiation codon. [provided by RefSeq] |
| Synonyms | ARMET antibody, ARP antibody, MGC142148 antibody, MGC142150 antibody, MANF antibody, mesencephalic astrocyte-derived neurotrophic factor antibody, "arginine-rich, mutated in early stage tumors antibody" |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human ARMET. The exact sequence is proprietary. |
| Antigen Species | Human |
| Species Reactivity | Human |
Predicted Cross Reactivity species  Predicted cross-reactivity:
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
| Mouse, Zebrafish, Pig, Bovine |
| Predict Reactivity Note | Mouse (99%), Zebrafish (84%), Pig (100%), Bovine (98%) |
| Conjugation | Unconjugated |